A picture of a shrimp.

Marine Genomics Consortium

Researchers from institutions across South Carolina are joining together to investigate marine organisms and foster collaboration among genomic, computational biology and proteomic fields. The mission is to use cyber-enabled genomic and bioinformatic approaches to predict and address the impact of climate change and environmental stressors on ecosystems.
Website: Marine Genomics Consortium Home Page

A young green chestnut burr

Genomic Tool Development for the Fagaceae

Description: A multi-institutional NSF funded grant to provide genomic tools for the Fagaceae family of trees. The outcomes will be construction of BAC libraries, sanger-style BAC-end and EST sequencing and the construction of an integrated physical and genetic map.
Investigator: Dr. Jeff Tomkins
Website: http://www.fagaceae.org

green, red, and yellow microarray spots

Chen Lab Research: Bioinformatics, Functional Genomics and Macrophage Signaling

Chen lab research centers on understanding how cells communicate, with a focus on signal transduction by human macrophages and the host-pathogen interaction. The laboratory currently emphasizes two approaches: functional genomics (including bioinformatics and computation) and molecular genetics/molecular biology.
Investigator: Dr. Chin-Fu Chen
Website: Chen Lab Home Page

gene network

Gene Co-Expression Networks

By combining co-expression networks with additional biological data, the Feltus lab is discovering and validating gene sub-networks that describe groups of coordinated genes with a common function such as the expression of a quantitative phenotype (e.g. QTL). In addition we are exploring how those networks have been modified to meet the physiological requirements of a particular species through comparative genome analysis.
Investigator: Dr. Alex Feltus
Website: Feltus Home Page

Jewel wasp

Comparative Genomics on the Insect Antennapedia Complex

ANT-C, the Antennapedia homeotic gene complex, contains anterior Hox genes that specify the identity of head and mouthpart segments.
Investigator: Monica Muñoz-Torres
Website: Nasonia Project Page

silversword

Adaptive Evolution in the Hawaiian Silversword Alliance

The Hawaiian silversword alliance provides an excellent, tractable system for understanding and connecting macro- and microevolutionary processes because it has undergone spectacular adaptive diversification despite minimal genetic differentiation.
Investigator: Dr. Amy Lawton-Rauh, Dept. of Genetics and Biochemistry
Website: Silversword Alliance Page

a cotton boll

Cotton Marker Database

This database provides centralized access to all publicly available SSRs from cotton as well as the standardized panel screened data for many of these microsatellites.
Investigator: Dr. Anna Blenda
Website: Cotton Marker Database Home Page

Purple Mimulus flower

Mimulus Fingerprinting and Sequencing

Due to tremendous ecological and phenotypic diversity, the genus Mimulus has been widely used as a superb model flowering plant system for ecological and evolutionary genetics.
Investigator: Dr. Jeff Tomkins
Website: Mimulus Project Page

Genomic Tool Development for the Fagaceae

The chestnut genome is being leveraged to learn more about North American hardwood trees such as Oak and Beech and to breed an American chestnut resistant to Chestnut Blight Disease.

green, red, and yellow microarray spots
Chen Lab Research: Bioinformatics, Functional Genomics and Macrophage Signaling

Chen lab research centers on understanding how cells communicate, with a focus on signal transduction by human macrophages and the host-pathogen interaction.

gene network
Gene Co-Expression Networks

The Feltus lab is combining co-expression networks with biological data to discover and validate sub-networks of coordinated genes with a common function.

A jewel wasp
Comparative Genomics on the Insect Antennapedia Complex

ANT-C, the Antennapedia homeotic gene complex, contains anterior Hox genes that specify the identity of head and mouthpart segments.

a silversword plant
Adaptive Evolution in the Hawaiian Silversword Alliance

The Hawaiian silversword alliance has undergone spectacular adaptive diversification despite minimal genetic differentiation.

a cotton boll
Cotton Marker Database

This database provides centralized access to all publicly available SSRs from cotton as well as the standardized panel screened data for many of these microsatellites.

a purple mimulus flower
Mimulus Fingerprinting and Sequencing

The genus Mimulus is a model organism for flowering plants. Its ecological and phenotypic diversity make it an exemplary candidate for ecological and evolutionary genetics.

a shrimp on the ocean floor
Marine Genomics Consortium

Researchers from institutions across South Carolina are joining together to investigate marine organisms and study the effects of warming ocean temperatures along the coast.